Radiological Properties of Selective Monomers of Polymer Gel Dosimeter in Radiotherapy Application

The basic radiation properties of the N-isopropylacrylamide based polymer gel dosimeter

Background: In this study the basic radiation properties of N-isopropylacrylamaide polymer gel dosimeter were determined together with verification of its soft tissue equivalency. Materials and Methods: The NIPAM gel was prepared and irradiated approximately 2 h after manufacturing. The magnetic resonance (MR) images were made 24 h after irradiation. The nuclear magnetic resonance (NMR) respons...

Evaluation of Gold Nanoparticle Size Effect on Dose Enhancement Factor in Megavoltage Beam Radiotherapy Using MAGICA Polymer Gel Dosimeter

Background: Gold nanoparticles (GNPs) are among the most promising radiosensitive materials in radiotherapy. Studying the effective sensitizing factors such as nanoparticle size, concentration, surface features, radiation energy and cell type can help to optimize the effect and possible clinical application of GNPs in radiation therapy. In this study, the radiation sensitive polymer gel was use...

Basic investigation on performance of low-density polymer gel dosimeter

Background:  In this study a series of basic dosimetric properties of a low-density (LD) gel dosimeter are investigated. The dose response is studied regarding to linearity, sensitivity, dose-rate and energy dependence as well as lung tissue equivalence. Materials and Methods: The LD gel was made by mixing the polymer gel with expanded polystyrene spheres. Energy dependence was studied...

Dosimetry and Radioenhancement Comparison of Gold Nanoparticles in Kilovoltage and Megavoltage Radiotherapy using MAGAT Polymer Gel Dosimeter

Background: Numerous unique characteristics of the nanosized gold, including high atomic number, low toxicity, and high biocompatibility make it one of the most appropriate nanostructures to boost radiotherapy efficacy. Many in-vivo and in-vitro investigations have indicated that gold nanoparticles (AuNPs) can significantly increase tumor injuries in low kilovoltage radiotherapy. While deep-lyi...

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